{"id":5102,"date":"2024-09-02T12:21:55","date_gmt":"2024-09-02T10:21:55","guid":{"rendered":"https:\/\/thoraxzentrum-ruhrgebiet.de\/publikacje-z-zakresu-onkologii-klatki-piersiowej\/"},"modified":"2026-10-21T14:41:33","modified_gmt":"2026-10-21T12:41:33","slug":"publikacje-z-zakresu-onkologii-klatki-piersiowej","status":"publish","type":"page","link":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/publikacje-3\/publikacje-z-zakresu-onkologii-klatki-piersiowej\/","title":{"rendered":"Publikacje z zakresu onkologii klatki piersiowej"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-7jn1tg-4b351f5482184b0db250ef62ebf81fea\">\n#top .av-special-heading.av-7jn1tg-4b351f5482184b0db250ef62ebf81fea{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-7jn1tg-4b351f5482184b0db250ef62ebf81fea .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-7jn1tg-4b351f5482184b0db250ef62ebf81fea .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-7jn1tg-4b351f5482184b0db250ef62ebf81fea av-special-heading-h1 blockquote modern-quote  avia-builder-el-0  el_before_av_textblock  avia-builder-el-first '><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Publikacje z zakresu onkologii klatki piersiowej<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n<section  class='av_textblock_section av-5cngzo-571dfc2a1e0011d0c4459db5af4aec58 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Tutaj znajd\u0105 Pa\u0144stwo informacje o naszych publikacjach w dziedzinie onkologii klatki piersiowej<\/p>\n<\/div><\/section>\n<div  class='togglecontainer av-4eu9jo-603240cd3a2a3c6bc6b8deedf6d536c7  avia-builder-el-2  el_after_av_textblock  avia-builder-el-last  toggle_close_all' >\n<section class='av_toggle_section av-30nmys-4341907d4dfcc320f9273f589b26364e'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{Wszystko} \"  ><p id='toggle-toggle-id-1' data-fake-id='#toggle-id-1' class='toggler  activeTitle av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-1' data-slide-speed=\"200\" data-title=\"Publikacje\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: Publikacje\" data-aria_expanded=\"Click to collapse: Publikacje\">Publikacje<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-1' aria-labelledby='toggle-toggle-id-1' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color '  itemprop=\"text\" ><p><strong>Prace oryginalne:<\/strong><br \/>\nPrace oryginalne:<\/p>\n<p><strong>2025<\/strong><br \/>\n1) Molasiotis A, Jordan K, Karthaus M, Dranitsaris G, Roeland EJ, Schwartzberg LS, Bonizzoni E, Brozos Vazquez E, Buchler T, Chen Y, Christoph DC, Garc\u00eda Alfonso P, Lu X, Majem M, Mavroudis D, Syrigos K, Tomlins E, Zhou Z, Zimovjanova M, Aapro MS (2025): Personalizing antiemetic prophylaxis for patients at high emetic risk: Results from the MyRisk Trial. Ann Oncol Volume 36 (Supplement): S1489-S1490, 2801O. Wyk\u0142ad na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>2) Metzenmacher M, Thomas M, Griesinger F, de Wit M, Christoph DC, Gro\u00df-Ophoff-M\u00fcller CS, J\u00e4nicke M, Fleitz A, Zacharias S, Groth A, Ludwig P , Kursar M, Fuchs C, Innig R, Dietze G, Dechow LT, Sebastian M, Eberhardt WE (2025): Combined chemo-immunotherapy versus monoimmunotherapy in advanced high PD-L1 positive NSCLC. Real-world data analyzed with propensity scores technique from the German prospective multicentre registry study (CRISP). Ann Oncol Volume 36 (Supplement): S1171, 2087eP. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>3) Eberhardt WEE, Passlick B, Groeschel A, Christoph DC, Grah C, Hoffknecht P, Ludwig P, Groth A, Lennartz C, Jaenicke M, Spring L, Seese B, Sebastian M, Griesinger F, Stuschke M, Thomas M (2025): Real-world treatment and outcome of patients with stage II-III NSCLC in Germany from 2018-24 (prospective German registry CRISP, AIO-TRK-0315). Ann Oncol Volume 36 (Supplement): S1060, 1841eP. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>4) Planchard D, S\u00e9bastien C, Mascaux C, Auliac J-B, Christoph DC, Bonomi L, Chella A, Carcereny E, Pons Tostivint E, Signorelli D, Beghdad F, Dialla O, Khan S, Popat S (2025): Diagnosis and treatment patterns in adults with metastatic non-small cell lung cancer with BRAF V600E mutation in clinical practice: An international ambispective real-world study (OCTOPUS). J Thorac Oncol Volume 20 Issue 3 (Supplement 1), 87P. Prezentacja plakatowa na World Conference on Lung Cancer 2025.<\/p>\n<p>5) Molassiotis A, Jordan K, Karthaus M, Dranitsaris G, Roeland EJ, Schwartzberg L, Stimamiglio V, Alonzi A, Tilola SO, Bonizzoni E, Brozos V\u00e1zquez E, Buchler T, Cheng Y, Christoph DC, Garc\u00eda Alfonso P, Lu X, Majem M, Mavroudis D, Syrigos K, Tomlins E, Zhou Z, Zimovjanov\u00e1 M, Aapro M (2025): Enhancing CINV Prevention: NEPA vs. Standard of Care in Patients with Multiple Emetic Risk Factors Receiving Moderately Emetogenic Chemotherapy (MEC). Prezentacja plakatowa na dorocznym zje\u017adzie Multinational Association of Supportive Care in Cancer (MASCC)\/ International Society for Oral Oncology (ISOC) 2025.<\/p>\n<p>6) Girard N, Bar J, Christoph D, Field J Fietkau R, Garassino MC, Garrido Lopez P, Haakensen VD, Hiltermann JTJN, Kao SC, McDonald F, Mornex F, Moskovitz MT, Peters S, Siva S, Solomon B, Qiao X, Anand S, Chander P, Filippi AR (2025): Real-world 5-year survival outcomes with durvalumab (D) after chemoradiotherapy (CRT) in unresectable, stage III NSCLC (urNSCLC): Final data extraction from PACIFIC-R. J Thorac Oncol Volume 30 Issue 2 (Supplement 1), 190P. Prezentacja plakatowa na European Lung Cancer Conference 2025.<\/p>\n<p>7) Planchard D, Couraud S, Mascaux C, Auliac JB, Christoph DC, Bonomi L, Chella A, Carcereny E, Pons-Tostivint E, Signorelli D, Beghdad F, Dialla O, Khan S, Popat S (2025): Diagnosis and treatment patterns in adults with metastatic non-small cell lung cancer with BRAF V600E mutation in clinical practice: An international ambispective real-world study (OCTOPUS). J Thorac Oncol Volume 30 Issue 2 (Supplement 1), 86P. Prezentacja plakatowa na European Lung Cancer Conference 2025<\/p>\n<p><strong>2024<\/strong><br \/>\n1) Kraus FM, Traut A, Nilius G, Volmerig J, Koziorowski A, St\u00f6ver I, Grabellus F, Stahl M, Christoph DC (2024): Pulmonary adenocarcinoma with enteric differentiation (PAED) without TTF-1 expression is a very rare subtype with limited treatment options and poor prognosis. Oncology w druku.<\/p>\n<p>2) Ferentinos K, Traut A, Gubelt L, Nilius G, Czyborra PB, Nusch A, Langer W, N\u00fcckel H, Hannig CV, Stahl M, Christoph DC (2024): Effectiveness and Safety of Docetaxel in Combination with Nintedanib or Ramucirumab Following Chemoimmunotherapy in Patients with Metastatic Non-Small-Cell Lung Cancer. J Oncol Res Ther 9: 10232. DOI: 10.29011\/2574-710X.10232.<\/p>\n<p>3) Kraus FM, Traut A, Gubelt L, Nilius G, Volmerig J, Koziorowski, St\u00f6ver I, Grabellus F, Stahl, M, Christoph DC (2024) Comparison of Single Agent Check-Point Inhibitors as First-Line Treatment in NSCLC Patients with High PD-L1-Expression. J Oncol Res Ther 9: 10228.<\/p>\n<p>4) Filippi AR, Bar J, Chouaid C, Christoph DC, Field JK, Fietkau R, Garassino MC, Garrido P, Haakensen VD, Kao S, Markman B, McDonald F, Mornex F, Moskovitz M, Peters S, Sibille A, Siva S, van den Heuvel M, Vercauter P, Anand S, Chander P, Licour M, de Lima AR, Qiao Y, Girard N (2024): Real-world outcomes with durvalumab after chemoradiotherapy in patients with unresectable stage III NSCLC: interim analysis of overall survival from PACIFIC-R. ESMO Open 9(6):103464.<\/p>\n<p>5) Neal J, Pavlakis N, Kim S-W, Goto Y, Lim SM, Mountzios G, Fountzilas E, Mochalova A, Christoph DC, Bearz A, Quantin X, Palmero R, Antic V, Chun E, Edubilli TR, Lin Y-C, Huseni M, Ballinger M, Graupner V, Curran D, Vervaet P, Newsom-Davis T (2024): CONTACT-01: A Randomized Phase III Trial of Atezolizumab + Cabozantinib Versus Docetaxel for Metastatic Non-Small Cell Lung Cancer After a Checkpoint Inhibitor and Chemotherapy. J Clin Oncol 42(20):2393-2403.<\/p>\n<p><strong>2023<\/strong><br \/>\n1) Borghaei H, de Marinis F, Dumoulin D, Reynolds C, Theelen WSME, Percent I, Gutierrez Calderon V, Johnson ML, Madroszyk-Flandin A, Garon EB, He H, Planchard D, Reck M, Popat S, Herbst RS, Leal TA, Shazer RL, Yan X, Harrigan R, Peters S; SAPPHIRE Investigators (2023): SAPPHIRE: phase III study of sitravatinib plus nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. Ann Oncol 35(1):66-76.<\/p>\n<p>2) Borchert S, Mathilakathu A, Nath A, Wessolly M, Mairinger E, Kreidt D, Steinborn J, Walter RFH, Christoph DC, Kollmeier J, Wohlschlaeger J, Mairinger T, Brcic L, Mairinger FD (2023). Cancer-Associated Fibroblasts Influence Survival in Pleural Mesothelioma: Digital Gene Expression Analysis and Supervised Machine Learning Model. Int J Mol Sci. 24(15):12426.<br \/>\n3) Stahl MK, Ertl SW, Engelmeyer P, Heuer HC, Christoph DC (2023): Impact of Geriatric Assessment on the Tolerability of Combination Chemotherapy in Older Patients with Advanced Cancer: A Matched-Pair Analysis. Oncol Res Treat. 46(3):100-105.<\/p>\n<p><strong>2022<\/strong><br \/>\n1) Girard N, Bar J, Garrido P, Garassino MC, McDonald F, Mornex F, Filippi AR, Smit HJM, Peters S, Field JK, Christoph DC, Sibille A, Fietkau R, Haakensen VD, Chouaid C, Markman B, Hiltermann TJN, Taus A, Sawyer W, Allen A, Chander P, Licour M, Solomon B (2022): Treatment Characteristics and Real-World Progression-Free Survival in Patients with Unresectable Stage III NSCLC who Received Durvalumab After Chemoradiotherapy: Findings from the PACIFIC-R Study. J Thorac Oncol. 18:181-193<\/p>\n<p>2) Zhang Z, Xie S, Cai W, Hong ZN, Yang C, Lin Y, Zhu J, Lin Z, Christoph DC, Bohnenberger H, Kepka L, Brueckl WM, Van Houtte P, Kang M, Lin J (2022): A nomogram to predict the recurrence-free survival and analyze the utility of chemotherapy in stage IB non-small cell lung cancer. Transl Lung Cancer Res. 11(1):75-86.<\/p>\n<p><strong>2021<\/strong><br \/>\n1) Mathilakathu A, Borchert S, Wessolly M, Mairinger E, Beckert H, Steinborn J, Hager T, Christoph DC, Kollmeier J, Wohlschlaeger J, Mairinger T, Schmid KW, Walter RFH, Brcic L, Mairinger FD (2021): Mitogen signal-associated pathways, energy metabolism regulation, and mediation of tumor immunogenicity play essential roles in the cellular response of malignant pleural mesotheliomas to platinum-based treatment: a retrospective study. Transl Lung Cancer Res 10(7):3030-3042.<\/p>\n<p>2) Metzenmacher M, Kopp HG, Griesinger F, Reinmuth N, Sebastian M, Serke M, Waller CF, Thomas M, Eggert J, Schmid-Bindert G, Hoiczyk M, Christoph DC, Kimmich M, Deu\u00df B, Seifert S, Held S, Schuler M, Herold T, Breitenbuecher F, Eberhardt WEE (2021): A randomized, multicenter phase II study comparing efficacy, safety and tolerability of two dosing regimens of cisplatin and pemetrexed in patients with advanced or metastatic non-small-cell lung cancer. Ther Adv Med Oncol. 13:1758835921996506.<\/p>\n<p>3) Zeuschner P, H\u00f6lters S, St\u00f6ckle M, Seliger B, Mueller A, Bachmann HS, Gr\u00fcnwald V, Christoph DC, Stenzl A, Grimm MO, Br\u00fcning F, Goebell PJ, Augustin M, Roos F, Harde J, Benz-R\u00fcd I, Staehler M, Junker K (2021): Thrombospondin-2 and LDH Are Putative Predictive Biomarkers for Treatment with Everolimus in Second-Line Metastatic Clear Cell Renal Cell Carcinoma (MARC-2 Study). Cancers (Basel) 13(11):2594.<br \/>\n4) Brcic L, Mathilakathu A, Walter RFH, Wessolly M, Mairinger E, Beckert H, Kreidt D, Steinborn J, Hager T, Christoph DC, Kollmeier J, Mairinger T, Wohlschlaeger J, Schmid KW, Borchert S, Mairinger FD (2021): Digital Gene Expression Analysis of Epithelioid and Sarcomatoid Mesothelioma Reveals Differences in Immunogenicity. Cancers (Basel) 13(8):1761.<\/p>\n<p>5) Ferdinandus J, Metzenmacher M, Kessler L, Umutlu L, Aigner C, Karl KO, Gr\u00fcnwald V, Eberhardt W, Fendler WP, Herrmann K, Faehling M, Christoph DC (2021): Complete metabolic response in patients with advanced nonsmall cell lung cancer with prolonged response to immune checkpoint inhibitor therapy. J Immunother Cancer 9(3):e002262.<\/p>\n<p>6) Frost N, Christopoulos P, Kauffmann-Guerrero D, Stratmann J, Riedel R, Schaefer M, Alt J, G\u00fctz S, Christoph DC, Laack E, Faehling M, Fischer R, Fenchel K, Haen S, Heukamp L, Schulz C, Griesinger F. (2021): Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program. Ther Adv Med Oncol. 13:1758835920980558.<\/p>\n<p><strong>2020<\/strong><br \/>\n1)Faehling M, Schumann C, Christopoulos P, Hoffknecht P, Alt J, Horn M, Eisenmann S, Schlenska-Lange A, Sch\u00fctt P, Steger F, Br\u00fcckl WM, Christoph DC (2020). Durvalumab after definitive chemoradiotherapy in locally advanced NSCLC: Data of the German EAP. Data Brief 34:106556.<\/p>\n<p>2)Faehling M, Schumann C, Christopoulos P, Hoffknecht P, Alt J, Horn M, Eisenmann S, Schlenska-Lange A, Sch\u00fctt P, Steger F, Br\u00fcckl WM, Christoph DC (2020): Durvalumab after definitive chemoradiotherapy in locally advanced unresectable non-small cell lung cancer (NSCLC): Real-world data on survival and safety from the German expanded-access program (EAP). Lung Cancer 150:114-122.<\/p>\n<p>3)Staehler M, St\u00f6ckle M, Christoph DC, Stenzl A, Potthoff K, Grimm MO, Klein D, Harde J, Br\u00fcning F, Goebell PJ, Augustin M, Roos F, Benz-R\u00fcd I, Marschner N, Gr\u00fcnwald V (2020): Everolimus after failure of one prior VEGF-targeted therapy in metastatic renal cell carcinoma: Final results of the MARC-2 trial. Int J Cancer, 148(7):1685-1694.<\/p>\n<p>4)Jia Z, Wang Y, Cao L, Wang Y, Song Y, Yang X, Bing Z, Cao Z, Liu P, Zhang S, Chen Z, Huang M, Yu Y, Han-Zhang H, Song J, Christoph DC, Passaro A, Gridelli C, Hishida T, Liang N, Li S (2020): First-line treatment selection with organoids of an EGFRm + TP53m stage IA1 patient with early metastatic recurrence after radical surgery and follow-up. J Thorac Dis. 12(7):3764-3773.<\/p>\n<p>5)Ferdinandus J, Barbato F, Chodyla M, Fendler WP, Kessler L, Pomykala KL, Metzenmacher M, Krefting F, Hager T, Umutlu L, Herrmann K, Christoph DC (2020): Volumetric PET response assessment outperforms conventional criteria in patients receiving high-dose pembrolizumab for malignant mesothelioma. J Nucl Med., 62(2):191-194.<\/p>\n<p><strong>2019<\/strong><br \/>\n1)Walter RFH, Sydow SR, Berg E, Kollmeier J, Christoph DC, Christoph S, Eberhardt WEE, Mairinger T, Wohlschlaeger J, Schmid KW, Mairinger FD (2019): Bortezomib sensitivity is tissue dependent and high expression of the 20S proteasome precludes good response in malignant pleural mesothelioma. Cancer Manag Res. 11:8711-8720.<\/p>\n<p>2)Krefting F, Basara N, Sch\u00fctte W, Sp\u00e4th-Schwalbed E, Alt J, Thiel S, Kimmich G, Fischer JR, Kurz S, Griesinger F, Christoph DC (2019): Clinical Experience of Immunotherapy Treatment: Efficacy and Toxicity Analysis of the Compassionate Use Program of Nivolumab in Patients with Advanced Squamous Cell Non-Small Cell Lung Cancer. J Cancer Res Clin Oncol. 42(5):243-255.<\/p>\n<p>3Walter RFH, Vollbrecht C, Werner R, Borchert S, Schmeller J, Mairinger E, Herold T, Streubel A, Christoph DC\u200e, Mairinger T, Schmid KW, Wohlschl\u00e4ger J, Hager T, Mairinger F (2019): Processing escape mechanisms through altered proteasomal cleavage of epitopes affect immune response in pulmonary neuroendocrine tumors. Technol Cancer Res T, 17: 1533033818818418.<\/p>\n<p>4)Borchert S, Wessolly M, Schmeller J, Mairinger E, Kollmeier J, Hager T, Mairinger T, Herold T, Christoph DC, Walter RFH, Eberhardt WEE, Pl\u00f6nes T, Wohlschlaeger J, Aigner C, Schmid KW, Mairinger FD (2019): Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro. BMC Cancer 19(1):108.<\/p>\n<p><strong>2018<\/strong><br \/>\n1)Stratmann JA, Michels S, Hornetz S, Christoph DC, Sackmann S, Spengler W, Bischoff H, Sch\u00e4fer M, Alt J, M\u00fcller A, Laack E, Kimmich M, Griesinger F, Sebastian M (2018): Efficacy and safety analysis of the German expanded access program of osimertinib in patients with advanced, T790M-positive non-small cell lung cancer. J Cancer Res Clin Oncol. 144(12):2457-2463.<\/p>\n<p>2)Oezkan F, Herold T, Darwiche K, Eberhardt WEE, Worm K, Christoph DC, Wiesweg M, Freitag L, Schmid KW, Theegarten D, Hager T, Koenig MJ, He K, Taube C, Schuler M, Breitenbuecher F. (2018): Rapid and Highly Sensitive Detection of Therapeutically Relevant Oncogenic Driver Mutations in EBUS-TBNA Specimens From Patients With Lung Adenocarcinoma. Clin Lung Cancer. 19(6):e879-e884.<\/p>\n<p>3)Walter RFH, Werner R, Wessolly M, Mairinger E, Borchert S, Schmeller J, Kollmeier J, Mairinger T, Hager T, Bankfalvi A, Christoph DC, Eberhardt WEE, Pl\u00f6nes T, Aigner C, Schmid KW, Wohlschlaeger J, Mairinger FD (2018): Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53. J Oncol. 2018:1986982.<\/p>\n<p>4)Mairinger FD, Schmeller J, Borchert S, Wessolly M, Mairinger E, Kollmeier J, Hager T, Mairinger T, Christoph DC, Walter RFH, Eberhardt WEE, Pl\u00f6nes T, Wohlschlaeger J, Jasani B, Schmid KW, Bankfalvi A (2018): Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy. Oncotarget. 9(32):22254-22268.<\/p>\n<p><strong>2017<\/strong><br \/>\n1)Peters S, Gettinger S, Johnson ML, J\u00e4nne PA, Garassino MC, Christoph D, Toh CK, Rizvi NA, Chaft JE, Carcereny Costa E, Patel JD, Chow LQM, Koczywas M, Ho C, Fr\u00fch M, van den Heuvel M, Rothenstein J, Reck M, Paz-Ares L, Shepherd FA, Kurata T, Li Z, Qiu J, Kowanetz M, Mocci S, Shankar G, Sandler A, Felip E (2017): Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1-Selected Advanced Non-Small-Cell Lung Cancer (BIRCH). J Clin Oncol. 35(24):2781-2789.<\/p>\n<p>2)Welter S, Arfanis E, Christoph D, Hager T, Roesel C, Aigner C, Weinreich G, Theegarten D (2017): Growth patterns of pulmonary metastases: should we adjust resection techniques to primary histology and size? Eur J Cardiothorac Surg. 52(1):39-46.<\/p>\n<p>3)Mairinger FD, Werner R, Flom E, Schmeller J, Borchert S, Wessolly M, Wohlschlaeger J, Hager T, Mairinger T, Kollmeier J, Christoph DC, Schmid KW, Walter RFH (2017): miRNA regulation is important for DNA damage repair and recognition in malignant pleural mesothelioma. Virchows Arch. 470(6):627-637.<\/p>\n<p>4)Mairinger FD, Vollbrecht C, Flom E, Christoph DC, Schmid KW, Kollmeier J, Popper HH, Mairinger T, Walter RFH (2017): Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma. Oncotarget. 8(23):37502-37510.<\/p>\n<p>5)Wiesweg M, Eberhardt WE, Reis H, Ting S, Savvidou N, Skiba C, Herold T, Christoph DC, Meiler J, Worm K, Kasper S, Theegarten D, Hense J, Hager T, Darwiche K, Oezkan F, Aigner C, Welter S, K\u00fchl H, Stuschke M, Schmid KW, Schuler M (2017): High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung Cancer. J Thorac Oncol. 12 (1):54-64.<\/p>\n<p><strong>2016<\/strong><br \/>\n1)Metzenmacher M &#038; Christoph DC (2016): Efficacy and safety of nivolumab combined with standard therapies for first-line therapy of advanced non-small cell lung cancer. J Thorac Dis. 8 (10), E1254-E1256.<\/p>\n<p>2)Walter RF, Werner R, Vollbrecht C, Hager T, Flom E, Christoph DC, Schmeller J, Schmid KW, Wohlschlaeger J, Mairinger FD (2016): ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology. PLoS One. 11 (11), e0165181.<\/p>\n<p>3)Walter RF, Vollbrecht C, Werner R, Mairinger T, Schmeller J, Flom E, Wohlschlaeger J, Barbetakis N, Paliouras D, Chatzinikolaou F, Adamidis V, Tsakiridis K, Zarogoulidis P, Trakada G, Christoph DC, Schmid KW, Mairinger FD (2016): Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy. J Cancer 7(13):1915-1925.<\/p>\n<p>4)Walter RF, Mairinger FD, Werner R, Vollbrecht C, Hager T, Schmid KW, Wohlschlaeger J, Christoph DC (2016): Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome. Oncotarget 7(15):20166-79.<\/p>\n<p>5)Walter RF, Vollbrecht C, Werner R, Wohlschlaeger J, Christoph DC, Kurt Werner S, Mairinger FD (2016): microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma. Oncotarget. 7(14):18713-18721.<\/p>\n<p>6)Fennell DA, Summers Y, Cadranel J, Benepal T, Christoph DC, Lal R, Das M, Maxwell F, Visseren-Grul C, Ferry D. (2016): Cisplatin in the modern era: The backbone of first-line chemotherapy for non-small cell lung cancer. Cancer Treat Rev 44:42-50.<\/p>\n<p><strong>2015<\/strong><br \/>\n7)Vollbrecht C, Werner R, Walter RF, Christoph DC, Heukamp LC, Peifer M, Hirsch B, Burbat L, Mairinger T, Kurt Werner S, Wohlschlaeger J, Mairinger FD (2015): Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group. Br J Cancer 113(12):1704-1711.<\/p>\n<p>8)Oezkan F, Khan AM, Hager T, Freitag L, Christoph D, Darwiche K (2015): OSNA: A Fast Molecular Test Based on CK19 mRNA Concentration for Assessment of EBUS-TBNA Samples in Lung Cancer Patients. Clin Lung Cancer. 17(3):198-204.<\/p>\n<p>9)Walter RF, Mairinger FD, Werner R, Ting S, Vollbrecht C, Theegarten D, Christoph DC, Zarogoulidis K, Schmid KW, Zarogoulidis P, Wohlschlaeger (2015): SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString). J. Future Oncol. 11(7):1027-1036.<\/p>\n<p>10)Reis H, Herold T, Ting S, Worm K, Huber U, Christoph DC, Eberhardt WE, Kostbade K, Kasper S, Stamatis G, Welter S, Darwiche K, Karpf-Wissel R, Theegarten D, Schmid KW, Schuler M, Wiesweg M (2015): HER2 expression and markers of phosphoinositide-3-kinase pathway activation define a favorable subgroup of metastatic pulmonary adenocarcinomas. Lung Cancer 88(1):34-41.<\/p>\n<p>11)Walter RF, Mairinger FD, Ting S, Vollbrecht C, Mairinger T, Theegarten D, Christoph DC, Schmid KW, Wohlschlaeger J (2015): MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14\/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53. Br J Cancer 112(5):883-890.<\/p>\n<p>12)Walter RF, Werner R, Ting S, Vollbrecht C, Theegarten D, Christoph DC, Schmid KW, Wohlschlaeger J, Mairinger FD (2015): Identification of deregulation of apoptosis and cell cycle in neuroendocrine tumors of the lung via NanoString nCounter expression analysis. Oncotarget. 6(28):24690-24698.<\/p>\n<p><strong>2014<\/strong><br \/>\n1)Mairinger FD, Walter RF, Theegarten D, Hager T, Vollbrecht C, Christoph DC, Worm K, Ting S, Werner R, Stamatis G, Mairinger T, Baba H, Zarogoulidis K, Huang H, Li Q, Tsakiridis K, Zarogoulidis P, Kurt Werner S &#038; Wohlschlaeger J (2014): Gene expression analysis of the 26S proteasome subunit PSMB4 reveals significant upregulation, different expression and association with proliferation in human pulmonary neuroendocrine tumours. J Cancer 5(8):646-654.<\/p>\n<p>2)Darwiche K, \u00d6zkan F, Ting S, Johnen G, Br\u00fcning T, Soltermann A, Huber LC, Christoph DC, Freitag L &#038; Franzen D (2014): Biomarkery raka p\u0142uc przed rozpocz\u0119ciem leczenia, ze szczeg\u00f3lnym uwzgl\u0119dnieniem procedur bronchoskopowych. Pneumologie 68 (11), 719-726.<\/p>\n<p>3)Mairinger FD, Walter RF, Werner R, Christoph DC, Ting S, Vollbrecht C, Zarogoulidis K, Huang H, Li Q, Schmid KW, Wohlschlaeger J &#038; Zarogoulidis P (2014): Activation of angiogenesis differs strongly between pulmonary carcinoids and neuroendocrine carinomas and is crucial for carcinoid tumourgenesis. J Cancer 5 (6), 465-471.<\/p>\n<p>4)Mairinger FD, Walter RF, Ting S, Vollbrecht C, Kollmeier J, Griff S, Hager T, Mairinger T, Christoph DC, Theegarten D, Kurt Werner S &#038; Wohlschlaeger J (2014): Mdm2 protein expression is strongly associated with survival in malignant pleural mesothelioma. Future Oncol. 10 (6), 995-1005.<\/p>\n<p>5)Christoph DC, Reyna-Asuncion B, Hassan B, Tran C, Maltzman JD, O\u2019Shannessy DJ, Gauler TC, Wohlschlaeger J, Schuler M, Eberhardt WE &#038; Hirsch FRH (2014). Assessment of Folate Receptor alpha and Epidermal Growth Factor Receptor Expression in Pemetrexed-Treated Non-Small Cell Lung Cancer Patients Clin Lung Cancer 15 (5), 320-330.<\/p>\n<p>6)Mairinger FD, Ting S, Werner R, Walter RF, Hager T, Vollbrecht C, Christoph D, Worm K, Mairinger T, Sheu-Grabellus SY, Theegarten D, Schmid KW &#038; Wohlschlaeger J (2014): Different micro-RNA expression profiles distinguish subtypes of neuroendocrine tumors of the lung: results of a profiling study. Mod Pathol. 27 (12), 1623-1640.<\/p>\n<p>7Nensa F, Stattaus J, Morgan B, Horsfield MA, Soria JC, Besse B, Gounant V, Khalil A, Seng K, Fischer B, Krissel H, Laurent D, Christoph D, Eberhardt WE &#038; Gauler TC (2014): Dynamic contrast-enhanced MRI parameters as biomarkers for the effect of vatalanib in patients with non-small-cell lung cancer. Future Oncol. 10 (5), 823-333.<\/p>\n<p>8)Christoph DC &#038; Eberhardt WE (2014): Systemic treatment of malignant pleural mesothelioma: new agents in clinical trials raise hope of relevant improvements. Curr Opin Oncol. 26 (2), 171-181.<\/p>\n<p><strong>2013<\/strong><br \/>\n1)Eberhardt WEE, Hoiczyk M &#038; Christoph DC (2013): Leczenie raka p\u0142uc. TumorDiagn u Ther. 34 (8), 449-452.<\/p>\n<p>2)Ting S, Mairinger FD, Hager T, Welter S, Eberhardt WE, Wohlschlaeger J, Schmid KW &#038; Christoph DC (2013): ERCC1, MLH1, MSH2, MSH6, and \u03b2III-tubulin: resistance proteins associated with response and outcome to platinum-based chemotherapy. Clin Lung Cancer 14 (5), 558-567.<\/p>\n<p>3)Gauler TC, Christoph DC, Fischer J, Frickhofen N, Huber R, Gonschorek C, Roth K, Giurescu M &#038; Eberhardt WEE (2013): Phase-I study of sagopilone (ZK-EPO) in combination with cisplatin in chemotherapy-naive patients with metastasised small-cell lung cancer. Eur J Cancer 49 (11), 2461-2468.<\/p>\n<p>4)Christoph DC &#038; Reckamp KL (2013): Intraventricular chemotherapy of leptomeningeal carcinomatosis from lung cancer \u2013 a feasible and beneficial treatment option? J Thorac Oncol. 8 (5), 523-524.<\/p>\n<p>5)Welter S, Schwan A, Cheufou D, Darwiche K, Christoph D, Eberhardt W, Weinreich G &#038; Stamatis G. (2013): Midterm changes in quality of life: a prospective evaluation after open pulmonary metastasectomy. Ann Thorac Surg. 95 (3), 1006-1011.<\/p>\n<p>6)Christoph DC, Reyna Asuncion B, Hassan B, Tran C, Maltzman JD, O\u2019Shannessy DJ, Wynes MW, Gauler TC, Wohlschlaeger J, Hoiczyk M, Schuler M, Eberhardt WEE &#038; Hirsch FR (2013): Significance of folate receptor alpha and thymidylate synthase expression in patients with non-small cell lung cancer treated with pemetrexed. J Thorac Oncol, 9 (1), 19-30.<\/p>\n<p><strong>2012<\/strong><br \/>\n7) Christoph DC, Reyna Asuncion B, Mascaux C, Tran C, Lu X, Wynes MW, Gauler TC, Wohlschlaeger J, Theegarten D, Neumann V, Hepp C, Welter S, Stamatis G, Tannapfel A, Schuler M, Eberhardt WEE &#038; Hirsch FR (2012): Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma. J Thorac Oncol. 7 (9), 1440-1448.<\/p>\n<p>8)Christoph DC, Kasper S, Gauler TC, Loesch C, Engelhard M, Theegarten D, Poettgen C, Hepp R, Peglow A, Loewendick H, Welter S, Stamatis G, Hirsch FR, Schuler M, Eberhardt WEE &#038; Wohlschlaeger J (2012): \u03b2V-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancer. Br J Cancer. 107 (5), 823-830.<\/p>\n<p>9)Wynes MW, Konopa K, Singh S, Asuncion BR, Ranger-Moore J, Sternau A, Christoph DC, Dzidziuszko R, Jassem J &#038; Hirsch FR (2012). Thymidylate Synthase protein expression by IHC and gene copy number by SISH correlate and show great variability in non-small cell lung cancer. J Thorac Oncol. 7 (6), 982-992.<\/p>\n<p>10)Christoph DC, Hoffmann, A-C, Gauler TC, Reyna Asuncion B, Loewendick H, Peglow A, Hassan B, Tran C, Wynes MW, Schuler M, Eberhardt WE &#038; Hirsch FR (2012). Detection of circulating lung cancer cells with strong thymidylate synthase reactivity in the peripheral blood of a patient with pulmonary adenocarcinoma treated with pemetrexed. J Thorac Oncol. 7 (4), 766-767.<\/p>\n<p><strong>2011<\/strong><br \/>\n1)Christoph DC &#038; Schuler M (2011). Plk1 inhibitors in mono- and combination therapies: a new strategy for treating malignancies. Expert Rev. Anticancer Ther. 11 (7), 1117-1132.<\/p>\n<p>2)Christoph DC, Witkowski L, Stattaus J, Poettgen C, Keyvani C, Gauler TC, Schuler M &#038; Eberhardt WEE (2011). Very late and isolated leptomeningeal relapse of a pulmonary adenocarcinoma presenting as dementia. Onkologie 34 (6), 316-320.<\/p>\n<p><strong>2009<\/strong><br \/>\n1)Christoph DC, Boese D, Johnson KT, Schlosser TW, Hunold P, Baba HA, Erbel R &#038; Philipp S (2009). Heart failure and cardiac involvement as isolated manifestation of familial form of transthyretin amyloidosis resulting from Val30Met mutation with no clinical signs of polyneuropathy. Circ Heart Fail. 2 (5), 512-515.<\/p>\n<p><strong>2004<\/strong><br \/>\n2)Keiper M, Stope MB, Szatkowski DC, B\u00f6hm A, Tysack K, vom Dorp F, Saur O, Oude Weernink PA, Evellin S, Jakobs KH &#038; Schmidt M. Epac- and Ca2+-controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors (2004). J Biol Chem. 279 (45), 46497-46508.<\/p>\n<p>3)Stope MB, vom Dorp F, Szatkowski DC, B\u00f6hm A, Keiper M, Nolte J, Oude Weernink PA, Rosskopf D, Evellin S, Jakobs KH &#038; Schmidt M (2004). Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3. Mol Cell Biol. 24 (11), 4664-4676.<\/p>\n<p><strong>Abstrakty i prezentacje na konferencjach:<\/strong><\/p>\n<p><strong>2024<\/strong><br \/>\n1) Shah R, Reck M, Grohe C, Christoph DC, Buchmeier EL, Saalfeld FC, Frost N, Kopp H-G, Faehling M, Griesinger F, Roeper J, Hoffknecht P, Kuon J, Luan J, Chesi P, Christopoulos P, Thomas M (2024): Efficacy of nivolumab\/ipilimumab as first-line treatment of pleural mesothelioma in the German real-world setting. J Clin Oncol 42, 2024 (suppl 16; abstr 8085). Prezentacja plakatowa na dorocznym zje\u017adzie American Society of Clinical Oncology.<\/p>\n<p>2) Hautzel H, Metzenmacher M, B\u00f6l\u00fckbas S, Volmerig J, Nilius G, Kersting D, Moka D, Herrmann K, Christoph D (2024): Tumorvolumetrische Parameter MTV und TLG zur Pr\u00e4diktion von progressionsfreiem und Gesamt-\u00dcberleben beim nicht-resektablen Malignen Mesotheliom unter Doppelimmuntherapie mit Ipilimumab und Nivolumab: Was kann die baseline FDG PET\/CT leisten? NuclearMedicine 63 (2), V06. Wyk\u0142ad na dorocznym zje\u017adzie Niemieckiego Towarzystwa Medycyny Nuklearnej.<\/p>\n<p>3) Christoph D, Metzenmacher M, B\u00f6l\u00fckbas S, Volmerig J, Nilius G, Moka D, Hautzel H (2024): PET-CT detects response to treatment with ipilimumab and nivolumab in malignant mesothelioma better than CT. Oncol Res Treat. Volume 47 (Supplement 1), P756. Prezentacja plakatowa na 36. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>4) Karthaus M, Christoph D, Lux MP, Hofheinz R-D, Jordan K (2024): Ocena korzy\u015bci p\u0142yn\u0105cych ze stosowania NEPA (sta\u0142e po\u0142\u0105czenie netupitantu\/palonosetronu) w zapobieganiu nudno\u015bciom i wymiotom wywo\u0142anym chemioterapi\u0105 (CINV) u pacjent\u00f3w z podwy\u017cszonym ryzykiem wymiot\u00f3w otrzymuj\u0105cych chemioterapi\u0119 o umiarkowanym dzia\u0142aniu emetogennym. Oncol Res Treat. Volume 47 (Supplement 1), P445. Prezentacja plakatowa na 36. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>5) Reitnauer L, Evers G, Christoph D, Br\u00fcckl W, Wiesweg M, Glanemann F, Webend\u00f6rfer M, Kropf-Sanchen C, Acker F, Sch\u00fctte W, Hoffknecht P, Kerkhoff A, Mohr M, Lenz G, Frost N, Overbeck T, Sebastian M, Bleckmann A (2024): Recurrence of locally advanced NSCLC after radiochemotherapy and consolidative Durvalumab &#8211; A german multicenter retrospective analysis. Oncol Res Treat. Volume 47 (Supplement 1), P947. Prezentacja plakatowa na 36. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>6) Ferentinos K, Volmerig J, Nilius G, Jaeger B, Koziorowski A, Stoever I, Christoph DC (2024): Addressing systemic first line therapy of elderly lung cancer patients is critical. Oncol Res Treat. Volume 47 (Supplement 1), P755. Prezentacja plakatowa na 36. Niemieckim Kongresie Onkologicznym.<\/p>\n<p><strong>2023<\/strong><br \/>\n1) Christoph DCCC, Metzenmacher M, B\u00f6l\u00fckbas S, Volmerig4 J, Nilius G, Moka D, Hautzel H (2023): PET-CT detects response to treatment with ipilimumab and nivolumab in malignant mesothelioma far better than CT. Ann Oncol Volume 34 (Supplement 2): S1135-S1144, 2196P. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>2) Kuon JB, Blasi M, Kokowski K, Faehling4 M, Schuette W, Christoph DCC, Kimmich M, Engel-Riedel W, Fischer JR, Lehmann M, Ulmer M, Schuett P, Moosmann N, Meyer zum B\u00fcschenfelde C, Griesinger F, Schneider M, Behnisch R, Stenzinger A, Christopoulos P, Thomas M (2023): DURATION: A multicenter randomized phase II trial investigating sequential mono- (mCTX) or doublet-chemotherapy (dCTX) followed by durvalumab (D) in older or frail patients with advanced non-small cell lung cancer (NSCLC). Ann Oncol Volume 34 (Supplement 2): S755-S851, 1442P Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>3) Ferentinos K, Volmerig J, Nilius G, Jaeger B, Koziorowski A, Stoever I, Christoph DCCC (2023): Challenge of systemic first-line treatment of elderly lung cancer patients. Ann Oncol Volume 34 (Supplement 2): S755-S851, 1483P. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>4) Evers G, Reitnauer LE, Christoph DCCC, Brueckl WM, Wiesweg M, Glanemann F, Webendoerfer M, Kropf C, Acker F, Hund A, Sch\u00fctte W, Hoffknecht P, Kerkhoff A, Mohr M, Lenz G, Frost N, Overbeck TR, Sebastian M, Bleckmann A (2023): Treatment and clinical outcome in recurrent\/refractory locally advanced NSCLC following chemoradiotherapy and consolidative durvalumab. Ann Oncol Volume 34 (Supplement 2): S746-S754, 1300P. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>5) Karthaus M, Christoph DC, Lux MP, Hofheinz RD, Jordan K (2023): Assessing the Benet of NEPA (Fixed Combination of Netupitant\/Palonosetron) for preventing Chemotherapyinduced Nausea and Vomiting (CINV) in patients at increased emetic risk receiving moderately emetogenic chemotherapy. Oncol Res and Treat 2023, Volume 46 (Supplement 5), P724. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>6) Ferentinos K, Volmerig J, Nilius G, Jaeger B, Koziorowski A, Stoever I, Christoph D (2023): Systemic first line treatment of elderly patients with lung cancer: proper choice is difficult. Oncol Res and Treat 2023, Volume 46 (Supplement 5), P453. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>7) Reitnauer L, Evers G, Christoph D, Br\u00fcckl W, Wiesweg M, Glanemann F, Webend\u00f6rfer M, Kropf-Sanchen C, Acker F, Sch\u00fctte W, Hoff\u00acknecht P, Kerkho\u00ac A, Mohr M, Lenz G, Frost N, Overbeck T, Sebastian M, Bleckmann A (2023): Relapse after radiochemotherapy and consolidative Durvalumab in Stage III NSCLC \u2013 a retrospective analysis in a real-world setting. Oncol Res and Treat 2023, Volume 46 (Supplement 5), P451. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>8) Christoph D, Metzenmacher M, B\u00f6l\u00fckbas S, Volmerig J, Nilius G, Moka D, Hautzel H (2023): PET-CT detects response to treatment with ipilimumab and nivolumab in malignant mesothelioma far better than CT. Oncol Res and Treat 2023, Volume 46 (Supplement 5), P446. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>9) Peters S, Christoph DC, Field JK, Fietkau R, Filippi AR, Garassino M, Garrido P, McDonald F, Mornex F, Markman B, Solomon BJ, Anand S, Chander P, Qiao Y, Girard N (2023): Real-World Outcomes with Durvalumab After Chemoradiotherapy in Unresectable Stage III EGFRMutated NSCLC (PACIFIC-R) J Thorac Oncol Volume 18 Issue 11 (Supplement), OA17.03. Wyk\u0142ad na World Conference on Lung Cancer 2023.<\/p>\n<p>10) Neal J, Pavlakis N, Kim S-W, Goto Y, Lim SM, Mountzios G, Fountzilas E, Mochalova A, Christoph DC, Bearz A, Quantin A, Palmero R, Antic V, Chun E, Rao Edubilli T, Lin Y-C, Huseni M, Scheffold C, Vervaet P, Newsom-Davis T (2023): CONTACT-01: Efficacy and safety from a phase III study of atezolizumab (atezo) + cabozantinib (cabo) vs docetaxel (doc) monotherapy in patients (pts) with metastatic NSCLC (mNSCLC) previously treated with checkpoint inhibitors and chemotherapy. Journal of Thoracic Oncology, Volume 18 Issue 4, S39 &#8211; S40. Wyk\u0142ad na European Lung Cancer Conference 2023.<\/p>\n<p><strong>2022<\/strong><br \/>\n1) Girard N, Christoph DCC, Garassino MC, McDonald F, Mornex F, Field JK, Fietkau R, Garrido Lopez P, Haakensen VD, Siva S, Van den Heuvel M, Bar J, Chouaid C, Vercauter P, Chander P, Licour M, Anand S, de Lima ARMD, Filippi ARR (2022): Real-world overall survival (OS) with durvalumab (D) after chemoradiotherapy (CRT) in patients (pts) with unresectable Stage III non-small-cell lung cancer (NSCLC): interim analysis from the PACIFIC-R study. Ann Oncol Volume 16 (Supplement 1), O580. Prezentacja plakatowa na European Society of Medical Oncology Immuno-Oncology Congress 2022.<\/p>\n<p>2) Galuba J, St\u00f6ver I, Koziorowski A, B\u00f6l\u00fckbas S, Nilius G, Christoph D (2022): Safety and efficacy of simultaneously performed radiotherapy in patients with small-cell lung cancer undergoing atezolizumab treatment. Oncol Res Treat. Volume 45 (Supplement 3), P606. Prezentacja plakatowa na 35. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>3) Wessolly M, Mathilakathu A, Mairinger E, Nath A, Beckert H, Kreidt D, Klopp N, Heged\u00fcs B, Steinborn J, Hager T, Walter RFH, Christoph DC, Kollmeier J, Wohlschlaeger J, Mairinger T, Brcic L, Borchert S, Schmid KW, FD Mairinger (2022): Signaling pathways linked to activity of cancer-associated fibroblasts lead to cancer progression and increased tumor cell motility in malignant pleural mesothelioma. Oncol Res Treat. Volume 45 (Supplement 3) P416. Prezentacja plakatowa na 35. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>4) Kraus F, Nilius G, B\u00f6l\u00fckbas S, St\u00f6ver I, Koziorowski A, Grabellus F, Christoph DC (2022): Clinical and pathological features and prognosis of non-small cell lung cancer (NSCLC) patients with adenocarcinomas without TTF1 and Napsin A expression. Oncol Res Treat. Volume 45 (Supplement 3), P433. Prezentacja plakatowa na 35. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>5) Christoph D, Girard N, Smit H.J.M, Sibille A, Mcdonald F, Mornex F, Garassino MC, Filippi AR, Peters S, Field JK, Drageset Haakensen V, Bar J, Chouaid C, Bray V, Kao S, Sawyer W, Allen A; Licour M, Garrido P, Fietkau R (2022): Pacific-R Real-World Study: Treatment Duration and Interim Analysis of Progression-Free Survival in Unresectable Stage III NSCLC Patients Treated with Durvalumab After Chemoradiotherapy. Oncol Res Treat. Volume 45 (Supplement 3), P256. Prezentacja plakatowa na 35. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>6) Gr\u00f6schel A, Passlick B, Stuschke M., Christopoulos P, Reck M, Grah C, Groth A, Hipper A, Chiabudini M, Fleitz A, J\u00e4nicke M, Spring L, Christoph D, Bernhardt C, Reiser M, M.-O. Zahn M-O, Sebastian M, Griesinger F, Thomas M, Eberhardt W (2022): Clinical Research platform Into molecular testing, treatment and outcome of non-Small cell lung carcinoma Patients (CRISP): First Real-World Evidence of NSCLC Stage II and III in Germany &#8211; AIO-TRK-0315. Oncol Res Treat. Volume 45 (Supplement 3), P135. Prezentacja plakatowa na 35. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>7) Zeuschner P, H\u00f6lters S, St\u00f6ckle M, Seliger B, M\u00fcller A, Bachmann HS, Gr\u00fcnwald V, Christoph DC, Stenzl A, Grimm M-O, Br\u00fcning F, Goebell PJ, Augustin M, Roos F, Harde J, Benz-R\u00fcd I, St\u00e4hler M, Junker K (2022): Thrombospondin-2 and LDH: potential predictive biomarkers for the treatment of metastatic renal cell carcinoma with everolimus after one VEGF-targeted therapy (MARC-2 study). Oncol Res Treat. Volume 45 (Supplement 3), P128. Prezentacja plakatowa na 35. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>8) Eberhardt W, Passlick B, Stuschke M, Gr\u00f6schel A, Christopoulos P, Reck M, Ludwig P, Hipper A, Chiabudini M, Spring L, J\u00e4nicke M, Andres-Pons A, Christoph DC, Bernhardt C, Reiser M, Sebastian M, Griesinger F, Thomas M (2022): V899 Kliniczna platforma do badania test\u00f3w molekularnych, leczenia i przebiegu choroby u pacjent\u00f3w z rakiem p\u0142uc (CRISP): Real-World Evidence dotycz\u0105ca pacjent\u00f3w z NSCLC leczonych radiochemioterapi\u0105 w Niemczech &#8211; AIO-TRK-0315. Oncol Res Treat. Volume 45 (Supplement 2), V899. Wyk\u0142ad na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>9) Sebastian M, Reck M, Fischer R, Christoph DC, Bernhardt C, von der Heyde E, Nusch A, Ludwig P, Hipper A, Hanselmann J, Medinger T, Binninger A, J\u00e4nicke M, Christopoulos P, Elender C, Bethge A, Seese B, Gauler T, Waller CF (2022): P327 Pierwsze dane Real-World Outcome pacjent\u00f3w z SCLC w Niemczech \u2013 dane z Clinical Research platform Into molecular testing, treatment and outcome of (non-)Small cell lung carcinoma Patients (CRISP; AIO-TRK-0315). Oncol Res Treat. Volume 45 (Supplement 2), P327. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>10) Passlick B, Stuschke M, Gr\u00f6schel A, Christopoulos P, Reck M, Grah C, Hoffknecht P, Ludwig P, Hipper A, Chiabudini M, Spring L, J\u00e4nicke M, Andres-Pons A, Christoph DC, Bernhardt C, Reiser M, Nusch A, Sebastian M, Griesinger F, Thomas M, Eberhardt W (2022): Clinical Research platform Into molecular testing, treatment and outcome of non-Small cell lung carcinoma Patients (CRISP): Real-World Evidence of NSCLC Stage I, II and III in Germany \u2013 AIO-TRK-0315. Zentralblatt f\u00fcr Chirurgie 147 (S01). V-130. Wyk\u0142ad na dorocznym zje\u017adzie DGT.<\/p>\n<p>11) Sebastian M, Reck M, Fischer RN, Christoph DC, Bernhardt C, von der Heyde E, Nusch A, Ludwig P, Hipper A, Hanselmann J, Medinger T, Binninger A, J\u00e4nicke M, Christopoulos P, Elender C, Bethge A, Seese B, Gauler TC, Waller C (2022). First real-world outcome data of SCLC in Germany: Data from the Clinical Research platform Into molecular testing, treatment and outcome of (non-)Small cell lung carcinoma Patients (CRISP; AIO-TRK-0315). Ann Oncol. 33 (S7), P1542. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>12) Kuon JB, Blasi M, Kokowsk K, Faehling M, Schuette W, Christoph DC, Kimmich M, Engel-Riedel W, Fischer J, Lehmann M, Ulmer M, Schuett P, Moosmann N, Meyer zum Bueschenfelde C, Griesinger F, Schneider M, Behnisch R, Stenzinger A, Christopoulos P, Thomas M (2022): DURATION &#8211; a phase II randomized trial in older \/ frail patients (pts) with advanced non-small cell lung cancer (NSCLC) comparing chemotherapy (CTX, 4 cycles) with CTX (2 cycles) and consecutive durvalumab (D): Top-line early efficacy endpoints. Ann Oncol. 33 (S7), P1021. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>13) Eberhardt WEE, Passlick B Stuschke M, Groeschel A, Christopoulos P Reck M, Ludwig P, Hipper A, Chiabudini M, Spring L, J\u00e4nicke M, Andres-Pons A, Christoph DC, Bernhardt C, Reiser M, Sebastian M, Griesinger F, Thomas M (2022): Clinical research platform Into molecular testing, treatment and outcome of non-Small cell lung carcinoma Patients (CRISP): Real-world evidence of NSCLC patients treated with radiochemotherapy in Germany \u2013 AIO-TRK-0315. Ann Oncol. 33 (S7), P963. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>14) Stuschke M, Eberhardt W, Passlick B, Groeschel A, Christopoulos P, Reck M, Grah C, Hoffknecht P, Ludwig P, Hipper A, Chiabudini M, Spring L, Jaenicke M, Andres-Pons A, Christoph DC, Bernhardt C, Reiser M, Nusch A, Sebastian M, Griesinger F, Thomas M (2022): EP05.01-030 CRISP: First Real-World Evidence of NSCLC Stage I, II and III in Germany &#8211; AIO-TRK-0315. J Thorac Oncol. Volume 17, Issue 9, Supplement. EP05.01. Prezentacja plakatowa na World Conference on Lung Cancer 2022.<\/p>\n<p><strong>2021<\/strong><br \/>\n1) Kuon J, Blasi M, Kokowski K, Faehling M, Sch\u00fctte W, Christoph DC, Kimmich M, Engel-Riedel W, Fischer JR, Lehmann M, Ulmer M, Schuett P, Moosmann N, Meyer zum B\u00fcschenfelde C, Griesinger F, Fischer von Weikersthal L, Schmidt B, Gleiber W, Kirchen H, Werke M, R\u00fcckert A, Fr\u00f6hling K-P, Schmidtke-Schrezenmeier G, Moulin J-C, Denzlinger C, B\u00f6sche M, Groh\u00e9 C, Bernhard H, Maintz C, Heinrich K, Kern J, Schneider MA, Krisam J, Sternsinger A, Thomas M (2021): Durvalumab in frail and older patients with stage IV non-small cell lung cancer: the randomized phase II DURATION trial. J Cancer Res Clin Oncol. Volume 44 (Supplement 2), ep641. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>2) Galuba JM, Imke S, Koziorowski A, B\u00f6l\u00fckbas S, Nilius G, Christoph DC (2021): Efficacy and safety of simultaneously performed radiotherapy in patients with small-cell lung cancer undergoing Atezolizumab treatment. Oncol Res Treat. Volume 44 (Supplement 2), ep577. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>3) Kraus F, Nilius G, B\u00f6l\u00fckbas S, St\u00f6ver I, Koziorowski A, Grabellus F, Christoph D (2021): Clinical and pathological features and prognosis of non-small cell lung cancer (NSCLC) patients with adenocarcinomas without TTF1 and Napsin A expression. Oncol Res Treat. Volume 44 (Supplement 2), ep573. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>4) Shah R, Klotz LV, Christoph DC, Ried M, Wehler T, Reck M, Wesseler C, Bethge A, de Wit M, Hoffknecht P, J\u00fcrgens J, Kopp H-G, Hackanson B, Waller CF, Reinmuth N, Schneider MA, Krisam J, Christopoulos P, Eichhorn ME, Thomas M (2021): Nivolumab with chemotherapy in pleural mesothelioma after surgery \u2013 NICITA. Oncol Res Treat.Volume 44 (Supplement 2), ep253. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>5) Christoph DC, Girard N, Smit HJM, Sibille A, McDonald F, Mornex F, Garassino MC, Filippi AR, Peters S, Field JK, Drageset Haakensen V, Bar J, Chouaid C, Bray V, Kao S, Sawyer W, Allen A, Licour M, Garrido P, Fietkau R (2021): Pacific-R real-world study: Treatment duration and interim analysis of progression-free survival in unresectable stage III NSCLC patients treated with Durvalumab after chemoradiotherapy. Oncol Res Treat.Volume 44 (Supplement 2), V495. Wyk\u0142ad na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>6) Eberhardt WEE, Passlick B, Stuschke M, Gr\u00f6schel A, Christopoulos P, Reck M, Grah C, Groth A, Hipper A, Chiabudini M, Fleitz A, J\u00e4nicke M, Spring L, Christoph DC, Bernhardt C, Reiser M, Zahn M-O, Sebastian M, Griesinger F, Thomas M, CRISP Registry Group (2021): Clinical research platform Into molecular testing, treatment and outcome of non-Small cell lung carcinoma patients (CRISP): First real-world evidence of NSCLC Stage II and III in Germany &#8211; AIO-TRK-0315: J Cancer Res Clin Oncol. Volume 44 (Supplement 2), V288. Wyk\u0142ad na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>7) Passlick B, Stuschke M, Gr\u00f6schel A, Christopoulos P, Reck M, Grah C, Groth A, Hipper A, Chiabudini M, Fleitz A, J\u00e4nicke M, Spring L, Christoph D, Bernhardt C, Reiser M, Zahn M-O, Sebastian M, Griesinger F, Thomas M, Eberhardt W (2021): Clinical Research platform Into molecular testing, treatment and outcome of non-Small cell lung carcinoma Patients (CRISP): First Real-World Evidence of NSCLC Stage II and III in Germany \u2013 AIO-TRK-0315. Zentralblatt f\u00fcr Chirurgie 146 (S01). V-122. Wyk\u0142ad na dorocznym zje\u017adzie DGT.<\/p>\n<p>8) Kraus F, Nilius G, B\u00f6l\u00fckbas S, St\u00f6ver I, Koziorowski A, Grabellus F, Christoph DC (2021): Clinical and pathological features and prognosis of nonsmall cell lung cancer (NSCLC) patients with adenocarcinomas without TTF1 and Napsin A expression. Ann Oncol. 32 (S5), P1812. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>9) Galuba JM, St\u00f6ver I, Koziorowski A, B\u00f6l\u00fckbas S, Nilius G, Christoph DC (2021): Safety of simultaneously performed radiotherapy in patients with small cell lung cancer undergoing atezolizumab treatment. Ann Oncol. 32 (S5), P1652. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>10) Gr\u00f6schel A, Passlick B, Stuschke M, Christopoulos P, Reck M, Grah C, Groth A, Hipper A, Chiabudini M, Fleitz A, J\u00e4nicke M, Spring L, Christoph DC, Bernhardt C, Reiser M, Zahn M-O, Sebastian M, Griesinger F, Thomas M, Eberhardt WEE (2021): Clinical research platform into molecular testing, treatment and outcome of non-small cell lung carcinoma patients (CRISP): First real-world evidence of NSCLC stage II and III in Germany &#8211; AIO-TRK-0315. Ann Oncol. 32 (S5), P1162. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>11) Girard N, Smit HJM, Sibille A, McDonald F, Mornex F, Garassino MCC, Filippi AR, Peters S, Field JK, Christoph DC, Fietkau R, Haakensen VD, Bar J, Chouaid C, Bray V, Kao S, Sawyer W, Allen A, Licour M, Garrido P (2021): PACIFIC-R real-world study: Treatment duration and interim analysis of progression-free survival in unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy. Ann Oncol. 32 (S5), MO1171. Kr\u00f3tki wyk\u0142ad na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>12) Galuba J, St\u00f6ver I, Koziorowski A, B\u00f6l\u00fckbas S, Nilius G, Christoph D (2021): Safety of Simultaneously Performed Radiotherapy in Patients With Small-Cell Lung Cancer Undergoing Atezolizumab Treatment. J Thorac Oncol. Volume 16, Issue 10, Supplement 1. P63.10. Prezentacja plakatowa na World Conference on Lung Cancer 2021.<\/p>\n<p>13) Kraus F, Nilius G, B\u00f6l\u00fckbas S, St\u00f6ver I, Koziorowski A, Grabellus F, Christoph D (2021): Pathological Features &#038; Prognosis of NSCLC Patients With Enteric Adenocarcinomas Without Expression of TTF-1 and Napsin A. J Thorac Oncol. Volume 16, Issue 10, Supplement 1. P56.04. Prezentacja plakatowa na World Conference on Lung Cancer 2021.<\/p>\n<p>14) Stuschke M, Passlick B, Gr\u00f6schel A, Christopoulos P, Reck M, Grah C, Groth A, Hipper A, Chiabudini M, Fleitz A, J\u00e4nicke M, Spring L, Christoph DC, Bernhardt C, Reiser M, Zahn M-O, Sebastian M, Griesinger F, Thomas M, Eberhardt WE (2021): Kliniczna platforma do bada\u0144 nad testowaniem molekularnym, leczeniem i przebiegiem choroby u pacjent\u00f3w z rakiem p\u0142uca (CRISP): pierwsze dane real-world dotycz\u0105ce NSCLC w stadium II i III w Niemczech &#8211; AIO-TRK-0315 (#175). Strahlentherapie und Onkologie Volume 197, supplement issue 1. VS01-2. Wyk\u0142ad na dorocznym zje\u017adzie DEGRO.<\/p>\n<p>15) Christoph DC, Ferdinandus J, Metzenmacher M, Kessler P, Umutlu L, Aigner C, Kambartel K-O, Gr\u00fcnwald V, Eberhardt WEE, Fendler WP, Herrmann K, Faehling M (2021). Complete metabolic response in advanced non-small cell lung cancer patients with prolonged response to immune checkpoint inhibitor therapy. Journal of Clinical Oncology 39:15 (supplement) 9050-9050. Dyskusja plakatowa na dorocznym zje\u017adzie American Society of Clinical Oncology.<\/p>\n<p>16) McDonald F, Mornex F, Garassino MC, Filippi AR, Christoph D, Haakensen VD, Agbarya A, Van den Heuvel M, Vercauter P, Chouaid C, Pichon E, Siva S, Steinbusch L, Peretz I, Solomon B, Decoster L, Sawyer W, Allen A, Licour M, Girard N (2021): PACIFIC-R: Real-world characteristics of unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy. J Thorac Oncol. Volume 16, Issue 4, Supplement 1. MO79. Kr\u00f3tki wyk\u0142ad na European Lung Cancer Conference 2021.<\/p>\n<p><strong>2020<\/strong><br \/>\n1)Shah R, Klotz LV, Fei\u00dft M, Schneider M, Kriegsmann M, Ried M, Wesseler C, Christoph DC, de Wit M, J\u00fcrgens J, Kopp H-G, Wehler T, Reck M, Sackmann S, Waller C, Reinmuth N, Bischoff H, Winter H , Eichhorn M, Thomas M (2020): NICITA: Nivolumab with chemotherapy in pleural mesothelioma after surgery. Ann Oncol. 31 (S4), TiP1912. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>2)Christoph DC, Rizzo F, Kambartel K-O, Winke S, Panse J, Abdulla DS, Scheffler M, Azeh IT, Hoiczyk M, Turki A, Metzenmacher M (2020): Docetaxel\/nindetanib as efficient treatment option after failure of immune checkpoint inhibition: Real-world evidence. Ann Oncol. 31 (S4), P1374. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>3)Christoph DC, Barbato F, Chodyla M-K, Fendler WP, Kessler L, Pomykala KL, Metzenmacher M, Krefting F, Hager T, Herrmann K, Ferdinandus J (2020): Volumetric PET response assessment outperforms conventional criteria in patients receiving high-dose pembrolizumab for malignant mesothelioma. Ann Oncol. 31 (S4), MO1896. Kr\u00f3tki wyk\u0142ad na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>4)Faehling M, Schumann C, Christopoulos P, Hoffknecht P, Alt J, Horn M, Eisenmann S, Schlenska -Lange A, Aries SP, Sackmann S, Schuett P, Steger F, Christoph D (2020): Durvalumab after definitive radiochemotherapy (RCT) in locally advanced unresectable NSCLC: Real-world data on survival and safety from the German expanded access program (EAP) Ann Oncol. 31 (S4), P1244. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>5)Girard N, Fietkau R, Garassino M, Garrido P, Field JK, Peters S, Smit HJM, P\u00e9rol M, Merle P, Sibille A, Markman B, Bouchaab H, Moskovitz M, Schumann C, Gregorc V, Klein AB, Diaz Perez I, Sawyer W, Licour M, Christoph D (2020): Characteristics of the first 615 patients enrolled in Pacific R: A study of the first real-world data on unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy. Ann Oncol. 31 (S4), P1242. Prezentacja plakatowa na dorocznym zje\u017adzie European Society of Medical Oncology.<\/p>\n<p>6)Ferdinandus J, Barbato F, Chodyla M, Fendler W, Kessler L, Metzenmacher M, Krefting F, Hager T, Herrmann K, Christoph D (2020): PERCIST-derived metabolic volume response predicts overall and progression-free survival in patients with malignant pleural mesothelioma treated with Pembrolizumab. Journal of Nuclear Medicine 61 (supplement 1) 243. Prezentacja plakatowa na dorocznym zje\u017adzie Society of Nuclear Medicine and Molecular Imaging 2020.<\/p>\n<p><strong>2019<\/strong><br \/>\n1)Christoph D, Behringer D, Emde TO, Goekkurt E, Hinske C, Laack E, M\u00fcller-H\u00fcssmann H, Schlenska-Lange A, Sch\u00fctt P, Schumann C, Seese B, Fietkau R (2019): PACIFIC-R: First real-world study of patients with unresectable, stage III NSCLC treated with durvalumab after chemoradiotherapy. Oncol Res Treat 42 (Suppl. 4), P757. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>2)Girard N, Mornex F, Christoph D, Fietkau R, Filippi A, Field J, Garrido Lopez P, McDonald F, Peters S, Klein A , Licour M, Garassino M (2019): PACIFIC-R: First real-world study of patients with unresectable, stage III NSCLC treated with durvalumab after chemoradiotherapy. TiP 101. Prezentacja plakatowa na European Lung Cancer Conference 2019.<\/p>\n<p>3)Christoph DC, Gettinger, S, Beck JT, Yang X, Telivala B, Morgensztern B, Velcheti V, Ramalingam S, Schalper K, Dajee M, Ranck A, Yang R, Spigel DR (2019): CheckMate 592: a phase 2 exploratory study of biomarkers associated with the efficacy of first-line nivolumab (nivo) plus ipilimumab (ipi) in patients (pts) with stage IV or recurrent NSCLC. Der Pneumologe, P618. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p><strong>2018<\/strong><br \/>\n1)Staehler M, Christoph D, St\u00f6ckle M, Harde J, Stenzl A, Klein D, Benz-R\u00fcd I, Gr\u00fcnwald V (2018): Final results of phase IV study MARC-2: everolimus after failure of one prior VEGFR-tyrosine kinase inhibitor therapy for metastatic renal cell carcinoma. J Cancer Res Clin Oncol. Volume 41 (Supplement 4), P610. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>2)Nadjm S, Exner JP, Gauler T, P\u00f6ttgen C, Darwiche K, Cheufou D, Krebs B, Metzenmacher M, Oezkan F, Rebmann V, Umutlu L, Deusch C, Li Y, Lahner H, Christoph D, Hoiczyk M, Witzke O, Hoffmann AC, Aigner C, Theegarten D, Taube C, Schuler M, Stamatis G, Stuschke M, Eberhardt W (2018): Long-term Survival(LTS) and Survivorship Program(SS-P) of Lung Cancer(LC) Patients(Pts). Investigations(Invest) on LT-toxicities(Tox) and late morbidities(Morb). J Cancer Res Clin Oncol. Volume 41 (Supplement 3), P436. Prezentacja plakatowa na 33. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>3)Mairinger F, Schmeller J, Wessolly M, Mairinger E, Borchert S, Kollmeier J, Hager T, Mairinger T, Christoph D, Walter R, Pl\u00f6nes T, Wohlschl\u00e4ger J, Jasani B, Schmid KW, Bankfalvi A (2018): Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy. J Cancer Res Clin Oncol. Volume 41 (Supplement 3), P406. Prezentacja plakatowa na 33. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>4)Mairinger F, Meier S, Wessolly M, K\u00f6hler C, Wagner F, Mairinger E, Schmeller J; Borchert S; Wohlschl\u00e4ger J, Pl\u00f6nes T, Hager T, Rozynek P, Kollmeier J, Christoph D, Schmid KW, Mairinger T, Johnen G, Walter R (2018): OncMass Spectrometry based Methylation Analysis of MDM2, CDKN2A, RB1, TP53 and TP73 and Associations to MDM2 Overexpression in Malignant Pleural mesothelioma. J Cancer Res Clin Oncol. Volume 41 (Supplement 3), P404. Prezentacja plakatowa na 33. Niemieckim Kongresie Onkologicznym.<\/p>\n<p>5)Mairinger FD, Schmeller J, Wessolly M, Mairinger E, Borchert S, Kollmeier J, Hager T, Christoph DC, Walter RFH, Eberhardt W, Pl\u00f6nes T, Wohlschl\u00e4ger J, Jasani B, Schmid KW, Bankfalvi A (2018): Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy. Pathologe 39 (suppl. 1), AG03.P.09. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>6)S. Borchert S, Wessolly M, Schmeller J, Mairinger E, Kollmeier J, Hager T, Mairinger T, Christoph DC; Walter RF, Bankfalvi A, Eberhardt WEE, Pl\u00f6nes T, Wohlschl\u00e4ger J, Aigner C, Schmid KW, Mairinger FD (2018): BRCAness Ph\u00e4notyp als potentieller pr\u00e4diktiver Marker f\u00fcr neue Therapie-Strategien beim Malignen Pleuramesotheliom. Pathologe 39 (suppl. 1), AG03.P.08. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>7)Wessolly M, Schmeller J, Mairinger E, Borchert S, Kollmeier J, Hager T, Mairinger T, Christoph DC, Walter RFH, Eberhardt WEE, Pl\u00f6nes8 T, Wohlschl\u00e4ger J, Schmid KW, Bankfalvi A, Mairinger1 FD (2018): miRNA regulation is important for DNA-damage repair and recognition in malignant pleural mesothelioma. Pathologe 39 (suppl. 1), AG-O303. Wyk\u0142ad na dorocznym zje\u017adzie DGP.<\/p>\n<p><strong>2017<\/strong><br \/>\n1)Stratmann JA, Hornetz S, Griesinger F, Wolf J, Christoph DC, Sackmann S, Spengler W, Bischoff H, Sch\u00e4fer M, Alt J, M\u00fcller A, Laack E, Kimmich M, Sebastian M (2017): An expanded access program of osimertinib (Tagrisso) in patients with advanced non-small cell lung cancer: data report from Germany. J Cancer Res Clin Oncol. Volume 40 (Supplement 3), P591. Prezentacja plakatowa na dorocznym zje\u017adzie DGHO, OeGHO i SGHSSH.<\/p>\n<p>2)Oezkan F, Herold T, Darwiche K, Eberhardt W, Christoph D, Worm K, Freitag L, Schmid K, Hager T, Breitenbuecher F, Schuler M (2017): Rapid and highly sensitive EGFR del ex19 and KRAS exon 2 mutation detection in EBUS-TBNA sspecimen of lung adenocarcinoma. J Thorac Oncol. Volume 11, Issue 11, Supplement 1. P3.02B-025. Prezentacja plakatowa na World Conference on Lung Cancer 2016<\/p>\n<p>3)Mairinger FD, Werner R, Flom E, Vollbrecht C, Schmeller J, Borchert S, Wohlschlaeger J, Mairinger T, Kollmeier J, Christoph DC, Schmid KW, Walter RFH (2017): miRNA regulation is important for DNA-damage repair and recognition in malignant pleural mesothelioma. Pathologe 38 (suppl. 1), P-702. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>4)Vollbrecht C, Werner R, Walter RFH, Christoph DC, Heukamp, LC, Peifer M, Hirsch B, Burbat L, Mairinger T, Schmid KW, Wohlschlaeger J, Mairinger FD (2017): Mutational analysis of pulmonary tumors with neuroendocrine features using targeted paralell sequencing. Pathologe 38 (suppl. 1), P-0606. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>5)Garassino M, Rizvi N, Besse B, J\u00e4nne P, Christoph D, Peters S, Toh CK, Kurata T, Costa EC, Koczywas M, Felip E, Chaft J, Qiu J, Kowanetz M, Coleman S, Mocci S, Sandler A, Gettinger S, Johnson M (2017): Atezolizumab as 1L therapy for advanced NSCLC in PD-L1\u2013selected patients: updated ORR, PFS and OS data from the BIRCH study. J Thorac Oncol. Volume 12 Issue 1, Supplement 1. OA03.02. Wyk\u0142ad na World Conference on Lung Cancer 2016.<\/p>\n<p><strong>2016<\/strong><br \/>\n1)Wakelee H, Patel JD, Heist R, Balmanoukian A, Besse B, Felip E, Costa EC, Chow LQ, Koczywas M, Garassino MC, Christoph D, Toh CK, Johnson ML, Chaft J, Kurata T, Qiu J, Kowanetz M, Coleman S, Mocci S, Sandler A, Gettinger SN, Peters S (2016): Phase II Trial of Atezolizumab for Patients with PD-L1\u2013Selected Advanced NSCLC (BIRCH): Updated Efficacy and Exploratory Biomarker Results. J Thorac Oncol. Volume 11, Issue 11, Supplement 1. ORAL01.04. Wyk\u0142ad na \u201eChicago Multidisciplinary Symposium in Thoracic Oncology\u201d 2016.<\/p>\n<p><strong>2015<\/strong><br \/>\n1) Walter RFH, Vollbrecht C, Christoph DC, Werner R, Mairinger T, Theegarten D, Schmid KW, Wohlschlaeger J, Mairinger FD (2015): Investigation of Pharmaceutical Targets in Pulmonary Neuroendocrine Tumors by massive parallel sequencing and digital gene expression analysis. Pathologe 36 (suppl. 1), SO-069. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>2)Walter RFH, Werner R, Vollbrecht C, Theegarten D, Worm K, Mairinger T, Wohlschlaeger J, Christoph DC, Mairinger FD (2015): Nutlin-3A key players are differentially regulated through miRNAs between MDM2-positive and -negative pleural mesotheliomas. Pathologe 36 (suppl. 1), SO-018. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>3)Walter RFH, Mairinger F, Werner R, Vollbrecht C, Mairinger T, Worm K, Schmid KW, Christoph DC, Wohlschl\u00e4ger J (2015): Molecular Biological Analysis of Malignant Pleural Mesothelioma. Pathologe 36 (suppl. 1), SO-071. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p><strong>2014<\/strong><br \/>\n1)Walter RFH, Mairinger FD, Werner R, Ting S, Vollbrecht C, Theegarten D, Stamatis G, Zwanziger D, Eberhardt W, Schuler M, Christoph DC, Freitag L, Schmid KW &#038; Wohlschlaeger J (2014): Screening 80 neuroendocrine lung cancer patients by using the NanoString technology implies several targets for new tailored therapies. Pathologe 35 (suppl. 1), SA-096. Prezentacja plakatowa na dorocznym zje\u017adzie DGP.<\/p>\n<p>2)Walter RFH, Mairinger FD, Ting S, Vollbrecht C, Hager T, Worm K, Eberhardt W, Kollmeier J, Mairinger T, Christoph DC, Schmid KW, Freitag L &#038; Wohlschlaeger J (2014): Inhibicja MDM2 poprzez Nutlin-3 \u2014 kolejna terapia z\u0142o\u015bliwego mi\u0119dzyb\u0142oniaka op\u0142ucnej o z\u0142ym rokowaniu? Pathologe 35 (suppl. 1), SA-095. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p>3)Mairinger F, Ting S, Werner R, Walter RFH, Hager T, Vollbrecht C, Christoph D, Worm K, Mairinger T, Sheu-Grabellus S-Y, Theegarten D, Schmid KW &#038; Wohlschlaeger J (2014): R\u00f3\u017cne profile ekspresji mikro-RNA rozr\u00f3\u017cniaj\u0105 podtypy guz\u00f3w neuroendokrynnych p\u0142uc: wyniki badania profilowania. Pathologe 35 (suppl. 1), SA-080. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p>4)Walter RFH, Mairinger FD, Werner R, Ting S, Vollbrecht C, Theegarten D, Stamatis G, Zwanziger D, Eberhardt W, Schuler M, Christoph DC, Freitag L, Schmid KW &#038; Wohlschlaeger J (2014): Czy profil ekspresji mRNA gen\u00f3w zwi\u0105zanych z apoptoz\u0105 i cyklem kom\u00f3rkowym jest markerem agresywno\u015bci guz\u00f3w neuroendokrynnych p\u0142uc? Pathologe 35 (suppl. 1), FR-048. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p>5)Mairinger F, Walter FRH, Werner R, Vollbrecht C, Ting S, Hager T, Schmid KW, Wohlschlaeger J &#038; Christoph D (2014): Metabolizm kwasu foliowego i naprawa niedopasowa\u0144 DNA w p\u0142ucnych guzach neuroendokrynnych: identyfikacja potencjalnych mechanizm\u00f3w oporno\u015bci na chemioterapi\u0119. Pathologe 35 (suppl. 1), FR-044. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p>6)Mairinger F, Walter RFH, Werner R, Ting T, Hager T, Vollbrecht C, Theegarten D, Christoph D, Schmid KW &#038; Wohlschlaeger J (2014): Aktywacja angiogenezy znacznie r\u00f3\u017cni si\u0119 mi\u0119dzy rakowiakami p\u0142uc a rakami neuroendokrynnymi i jest kluczowa dla karcynogenezy. Pathologe 35 (suppl. 1), FR-043. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p><strong>2013<\/strong><br \/>\n1)Mairinger F, Ting S, Vollbrecht C, Walter RFH, Kollmeier J, Grief S, Hager T, Mairinger T, Christoph D, Schmid KW &#038; Wohlschl\u00e4ger J (2013): Immunoekspresja homologu ligazy bia\u0142kowej ubikwityny P53 E3 (mysz) (MDM-2) jest silnym predyktorem s\u0142abego ca\u0142kowitego prze\u017cycia w z\u0142o\u015bliwym mi\u0119dzyb\u0142oniaku op\u0142ucnej. Pathologe 34 (suppl. 1), FR-103. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p>2)Mairinger F, Ting S, Worm K, Hager T, Wohlschl\u00e4ger J, Schmid KW &#038; Christoph D (2013): LH1, MSH2, MSH6 i ERCC1: bia\u0142ka naprawy niedopasowa\u0144 DNA zwi\u0105zane z odpowiedzi\u0105 na chemioterapi\u0119 opart\u0105 na platynie w MPM? Pathologe 34 (suppl. 1), FR-078. Prezentacja plakatowa na dorocznej konferencji DGP.<\/p>\n<p>3)Mairinger F, Walter RFH, Hager T, Vollbrecht C, Christoph D, Worm K, Ting S, Schmid KW &#038; Wohlschl\u00e4ger J (2013): Podjednostki proteasomu PSMA5 i PSMB4 s\u0105 silnymi markerami do rozr\u00f3\u017cniania typowych i atypowych guz\u00f3w rakowiakowych p\u0142uc. Pathologe 34 (suppl. 1), DO-036. Wyk\u0142ad na dorocznej konferencji DGP.<\/p>\n<p><strong>2012<\/strong><br \/>\n1)Christoph DC, Reyna Asuncion B, Hassan B, Maltzman J, O\u2019Shannessy D, Gauler TC, Wohlschlaeger J, Wynes MW, Schuler M, Eberhardt WEE &#038; Hirsch FR (2012): Znaczenie ekspresji receptora folianowego alfa (FRA) i syntazy tymidylanowej (TS) u pacjent\u00f3w z przerzutowym niedrobnokom\u00f3rkowym rakiem p\u0142uca leczonych chemioterapi\u0105 opart\u0105 na pemetreksedzie. Onkologie 36 (suppl. 6; abstr V125). Wyk\u0142ad na dorocznej konferencji DGHO, OeGHO i SGHSSH.<\/p>\n<p>2)Christoph DC, Reyna Asuncion B, Hassan B, Maltzman J, O\u2019Shannessy D, Gauler TC, Wynes MW, Schuler M, Eberhardt WEE &#038; Hirsch FR (2012): Badanie ekspresji bia\u0142ek receptora folianowego alfa i syntazy tymidylanowej u pacjent\u00f3w z przerzutowym niedrobnokom\u00f3rkowym rakiem p\u0142uca leczonych chemioterapi\u0105 opart\u0105 na pemetreksedzie. J Thorac Oncol 10 (Suppl 2). Wyk\u0142ad na \u201eChicago Multidisciplinary Symposium in Thoracic Oncology\u201d 2012.<\/p>\n<p>3)Christoph DC, Reyna Asuncion B, Wynes MW, Gauler TC, Wohlschlaeger J, Theegarten D, Welter S, Tran C, Hassan B, Loewendick H, Peglow A, Schuler M, Eberhardt WEE &#038; Hirsch FR (2012): Syntaza folilpoliglukonianowa i syntaza tymidylanowa s\u0105 zwi\u0105zane z wynikiem klinicznym terapii opartej na pemetreksedzie w zaawansowanym niedrobnokom\u00f3rkowym raku p\u0142uca (NSCLC). Abstrakt 1713. Prezentacja plakatowa na dorocznej konferencji American Association of Cancer Research.<\/p>\n<p>4)Christoph DC, Reyna Asuncion B, Wynes MW, Gauler TC, Wohlschlaeger J, Theegarten D, Welter S, Tran C, Hassan B, Loewendick H, Peglow A, Schuler M, Eberhardt WEE &#038; Hirsch FR (2012): Syntaza folilpoliglukonianowa i syntaza tymidylanowa s\u0105 zwi\u0105zane z wynikiem klinicznym terapii opartej na pemetreksedzie w zaawansowanym niedrobnokom\u00f3rkowym raku p\u0142uca (NSCLC). Plakat B6. Prezentacja plakatowa na wsp\u00f3lnej konferencji AACR-IASLC \u201eMolecular Origins of Lung Cancer: Biology, Therapy, and Personalized Medicine\u201d, San Diego, CA, USA.<\/p>\n<p><strong>2011<\/strong><br \/>\n1)Christoph DC, Kasper S, Gauler TC, Breitenbuecher F, Engelhard M, Theegarten D, Poettgen C, Hepp R, Peglow A, Loewendick H, Schuler M, Hirsch FR, Eberhardt WEE &#038; Wohlschlaeger J (2011): Ocena ekspresji betaV-tubuliny jako nowego predykcyjnego biomarkera korzy\u015bci klinicznych z leczenia taksanami w niedrobnokom\u00f3rkowym raku p\u0142uca. Eur J Cancer 47 (suppl 4; abstr PP35). Prezentacja plakatowa na dorocznej konferencji EORTC-NCI-ASCO \u201eMolecular Markers in Cancer\u201d.<\/p>\n<p>2)Gauler TC, Poettgen C, Korfee S, Wagner H, Hepp R, Stamatis G, Christoph DC, Passlick B, Budach V, Seeber S, Wilke H, Stuschke M &#038; Eberhardt W (2011): D\u0142ugoterminowe prze\u017cycie (LTS) i konkurencyjne ryzyka w prospektywnym, wieloo\u015brodkowym, niemieckim badaniu randomizowanym por\u00f3wnuj\u0105cym chemioterapi\u0119 indukcyjn\u0105 (IND) (CTx) z nast\u0119puj\u0105c\u0105 jednoczesn\u0105 (cc) chemioradioterapi\u0105 (CTx\/RTx) plus operacja (S) (=TRIMODALNO\u015a\u0106) uzupe\u0142nion\u0105 o PCI versus samo leczenie miejscowe (S + RTx) w operacyjnym NSCLC w stadium IIIA. J Thorac Oncol. 6 (suppl 2; abstr 2575). Mini-wyk\u0142ad na World Conference on Lung Cancer 2011.<\/p>\n<p>3)Poettgen C, Le Pechoux C, Gauler TC, Stuschke M, Grunenwald DH, Stamatis G, Bildat S, Krbek T, Christoph DC, Welter S, Fischer B, Hepp R, Theegarten D &#038; Eberhardt W (2011): 10-letnie d\u0142ugoterminowe prze\u017cycie (LTS) po chemioterapii indukcyjnej (IND) z trzema cyklami cisplatyny (P)\/paklitakselu (T), a nast\u0119pnie jednoczesnej (cc) chemioradioterapii (CTx\/RTx) P\/etopozyd (eto)\/45 Gy (1,5 Gy bid) plus operacja (S) \u2013 wieloo\u015brodkowe badanie fazy II (CISTAXOL). J Thorac Oncol. 6 (suppl 2; abstr 2.563). Mini-wyk\u0142ad na World Conference on Lung Cancer 2011.<\/p>\n<p>4)Christoph DC, Mascaux C, Wynes MW, Reyna Asuncion B, Wohlschlaeger J, Theegarten D, Gauler TC, Neumann V, Poettgen C, Tran C, Tannapfel A, Schuler M, Eberhardt WEE &#038; Hirsch FR (2011): Warto\u015b\u0107 predykcyjna syntazy tymidylanowej i syntazy folilpoliglukonianowej dla korzy\u015bci klinicznych z pemetreksedu w z\u0142o\u015bliwym mi\u0119dzyb\u0142oniaku op\u0142ucnej. J Thorac Oncol. 6 (suppl 2; abstr 2.480). Prezentacja plakatowa na World Conference on Lung Cancer 2011.<\/p>\n<p>5)Eberhardt W, Hepp R, Gauler TC, Christoph DC, Hoffmann A-C, Theegarten D, Welter S, Schmid KW, Wohlschlaeger J, Passlick B, Le P\u00e9choux C, Stamatis G, Stuschke M &#038; Poettgen C (2011): Analiza konkurencyjnych ryzyk i d\u0142ugoterminowe prze\u017cycie (LTS) pacjent\u00f3w (pts) z miejscowo zaawansowanym (LAD) niedrobnokom\u00f3rkowym rakiem p\u0142uca (NSCLC) w stadium III leczonych w sekwencyjnych badaniach trimodalnych (TM). J Thorac Oncol 6: 2011 (suppl 2; abstr 2.200). Wyk\u0142ad na World Conference on Lung Cancer 2011.<\/p>\n<p>6)Christoph DC, Wohlschlaeger J, Neumann V, Gauler TC, Poettgen C, Peglow A, Tannapfel A, Schuler M, Hirsch FR, Eberhardt WEE &#038; Theegarten D (2011): Wp\u0142yw ekspresji reduktazy dihydrofolianowej na korzy\u015bci kliniczne z pemetreksedu w z\u0142o\u015bliwym mi\u0119dzyb\u0142oniaku op\u0142ucnej. J Thorac Oncol. 6 (suppl 2; abstr 1.853). Prezentacja plakatowa na World Conference on Lung Cancer 2011.<\/p>\n<p>7)Christoph DC, Kasper S, Gauler TC, Breitenbuecher F, Engelhard M, Theegarten D, Poettgen C, Hepp R, Peglow A, Loewendick H, Schuler M, Hirsch FR, Eberhardt WEE &#038; Wohlschlaeger J (2011): Ocena ekspresji betaV-tubuliny jako nowego predykcyjnego biomarkera korzy\u015bci klinicznych z leczenia taksanami w niedrobnokom\u00f3rkowym raku p\u0142uca. J Thorac Oncol. 6 (suppl 2; abstr 2.227). Prezentacja plakatowa na World Conference on Lung Cancer 2011.<\/p>\n<p>8)Christoph DC, Mascaux C, Wynes MW, Reyna Asuncion B, Wohlschlaeger J, Theegarten D, Gauler TC, Schuler M, Eberhardt WEE &#038; Hirsch FR (2011): Warto\u015b\u0107 predykcyjna syntazy tymidylanowej i syntazy folilpoliglukonianowej dla korzy\u015bci klinicznych z pemetreksedu w z\u0142o\u015bliwym mi\u0119dzyb\u0142oniaku op\u0142ucnej. J Clin Oncol. 29 (suppl; abstr 7024). Dyskusja plakatowa na dorocznej konferencji American Society of Clinical Oncology.<\/p>\n<p>9)Christoph DC, Wittkowski L, Stattaus J, P\u00f6ttgen C, Keyvani K, Gauler TC, Schuler M &#038; Eberhardt WEE (2011): Bardzo p\u00f3\u017any i izolowany nawr\u00f3t leptomeningealny gruczolakoraka p\u0142uc objawiaj\u0105cy si\u0119 jako demencja. Onkologie 34 (suppl. 6; abstr P574). Prezentacja plakatowa na dorocznej konferencji DGHO, OeGHO i SGHSSH.<\/p>\n<p><strong>2009<\/strong><br \/>\n1)Gauler TC, Christoph DC, Gamarra F, Fuhr H-G, Gonschorek C, Giurescu M, Frickhofen N, Huber RM, Schuler M &#038; Eberhardt WEE (2008): Badanie fazy I sagopilonu (ZK-EPO) w po\u0142\u0105czeniu z cisplatyn\u0105 u pacjent\u00f3w z chemioterapeutycznie naiwnym rozleg\u0142ym drobnokom\u00f3rkowym rakiem p\u0142uca (ED-SCLC). Ann Oncol. 19 (suppl 1: abstr 331P). Prezentacja plakatowa na dorocznej konferencji European Cancer Organisation\/European Society of Medical Oncology.<\/p>\n<p>2)Christoph DC, Gauler TC, Gamarra F, Fuhr H-G, Fischer JR, Gonschorek C, Frickhofen N, Huber RM, Schuler M &#038; Eberhardt WEE (2009): Badanie fazy I sagopilonu w po\u0142\u0105czeniu z cisplatyn\u0105 jako terapia pierwszego rzutu u pacjent\u00f3w z rozleg\u0142ym drobnokom\u00f3rkowym rakiem p\u0142uca (ED-SCLC). Eur J Cancer Suppl. 7 (abstr Po9142). Prezentacja plakatowa na dorocznej konferencji European Cancer Organisation\/European Society OF Medical Oncology.<\/p>\n<p>3)Gauler TC, Christoph DC, Gamarra F, Fuhr H-G, Fischer JR, Gonschorek C, Giurescu M, Frickhofen N, Huber RM, Schuler M &#038; Eberhardt WEE (2009): Badanie fazy I sagopilonu (ZK-EPO) w po\u0142\u0105czeniu z cisplatyn\u0105 u pacjent\u00f3w z chemioterapeutycznie naiwnym rozleg\u0142ym drobnokom\u00f3rkowym rakiem p\u0142uca (ED-SCLC). J Thorac Oncol. 4 (suppl 1; abstr PD4.4.1). Dyskusja plakatowa na World Conference on Lung Cancer 2009.<\/p>\n<p><strong>2008<\/strong><br \/>\n1)Christoph DC, Gauler TC, Gamarra F, Fuhr H-G, Gonschorek C, Giurescu M, Frickhofen N, Huber RM, Schuler M &#038; Eberhardt WEE (2008): Badanie fazy I sagopilonu (ZK-EPO) w po\u0142\u0105czeniu z cisplatyn\u0105 jako terapia pierwszego rzutu u pacjent\u00f3w z rozleg\u0142ym drobnokom\u00f3rkowym rakiem p\u0142uca (ED-SCLC). Onkologie 31 (suppl. 4; abstr V180). Wyk\u0142ad na dorocznej konferencji DGHO, OeGHO i SGHSSH.<\/p>\n<p><strong>2004<\/strong><br \/>\n1)Schmidt M, Stope MB, Szatkowski DC, vom Dorp F, Oude Weernink PA &#038; Jakobs KH (2004): Epac i aktywacja Ras i kinaz regulowanych sygna\u0142em zewn\u0105trzkom\u00f3rkowym kontrolowana przez Ca2+ przez receptory sprz\u0119\u017cone z Gs. N-S Arch Pharmacol. 371 (suppl 1; abstr R10). Wyk\u0142ad na dorocznej konferencji DGPT 2003.<\/p>\n<p>2)Szatkowski DC, Keiper M, Stope MB, Oude Weernink PA, Jakobs KH &#038; Schmidt M (2004): Aktywacja Ras i kinaz MAP przez receptor \u03b22-adrenergiczny za po\u015brednictwem PLC-\u03b5 i CalDAG2. N-S Arch Pharmacol. 369 (suppl 1; abstr R203). Wyk\u0142ad na dorocznej konferencji DGPT.<\/p>\n<p><strong>2003<\/strong><br \/>\n1)Szatkowski DC, B\u00f6hm A &#038; Schmidt M (2003): Molekularne mechanizmy stymulacji fosfolipazy C-e przez EGF zale\u017cnej od CalDAG3 i Rap2B. Prezentacja plakatowa na 2. Dniu Bada\u0144 Klinicznych Uniwersyteckiego Szpitala w Essen (11-18-2003).<\/p>\n<p>2)Schmidt M, Keiper M, B\u00f6hm A, Evellin S, Sari A, Szatkowski DC, vom Dorp F, OudeWeernink, PA &#038; Jakobs KH (2003): Mechanizmy stymulacji fosfolipazy C za po\u015brednictwem CalDAG3 i Rap2B przez receptor nask\u00f3rkowego czynnika wzrostu. N-S Arch Pharmacol. 367 (suppl 1; abstr R195). Wyk\u0142ad na dorocznej konferencji DGPT.<\/p>\n<\/div><\/div><\/div><\/section>\n<section class='av_toggle_section av-m194jok1-e0afc5f830ef34ece86b54f1cf897fc9'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{Wszystko} \"  ><p id='toggle-toggle-id-2' data-fake-id='#toggle-id-2' class='toggler  av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-2' data-slide-speed=\"200\" data-title=\"Wk\u0142ady do ksi\u0105\u017cek\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: Wk\u0142ady do ksi\u0105\u017cek\" data-aria_expanded=\"Click to collapse: Wk\u0142ady do ksi\u0105\u017cek\">Wk\u0142ady do ksi\u0105\u017cek<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-2' aria-labelledby='toggle-toggle-id-2' role='region' class='toggle_wrap  av-title-above'  ><div class='toggle_content invers-color '  itemprop=\"text\" ><p><strong>2016<\/strong><br \/>\n1)Christoph DC &#038; Eberhardt WEE: Radioterapia u starszych pacjent\u00f3w z rakiem (Rozdzia\u0142 6). W: Schrijvers D, Aapro M, Zakotnik B, Audisio R, van Halteren H, Hurria A. EUROPEAN SOCIETY OF MEDICAL ONCOLOGY HANDBOOK OF CANCER IN THE SENIOR PATIENT (2016). Informa Healthcare New York \u2013 London.<\/p>\n<p><strong>2012<\/strong><br \/>\n1)Eberhardt WEE, Krbek T, Theegarten D &#038; Christoph DC: Z\u0142o\u015bliwy mi\u0119dzyb\u0142oniak (Rozdzia\u0142 19). W: Meyer J, Fleig WE, Pletz MW, Mayet W-J, Mertens P, M\u00fcller O-A, Pfeifer M, Weiss N &#038; Busse O. Racjonalna diagnostyka i terapia w medycynie wewn\u0119trznej. Wydanie 35 Elsevier Monachium.<\/p>\n<p><strong>2010<br \/>\n<\/strong>1)Christoph DC &#038; Eberhardt WEE: Radioterapia u starszych pacjent\u00f3w z rakiem (Rozdzia\u0142 6). W: Schrijvers D, Aapro M, Zakotnik B, Audisio R, van Halteren H, Hurria A. EUROPEAN SOCIETY OF MEDICAL ONCOLOGY HANDBOOK OF CANCER IN THE SENIOR PATIENT (2010). Informa Healthcare New York \u2013 London.<\/p>\n<p><strong>2007<\/strong><br \/>\n1)Christoph D &#038; Christoph S. Zaburzenia zdrowotne \u2013 Drogi moczowe (Rozdzia\u0142 10). W: Schaps K-P, Kessler O, Fetzner U. DAS ZWEITE \u2013 KOMPAKT (2007). Springer Heidelberg.<\/p>\n<p>2)Szatkowski D &#038; Schaps K-P. Medycyna wewn\u0119trzna \u2013 Hematologia, hemostazeologia i onkologia internistyczna (Rozdzia\u0142 7). W: Schaps K-P, Kessler O &#038; Fetzner U. DAS ZWEITE \u2013 KOMPAKT (2007). Springer Heidelberg.<\/p>\n<\/div><\/div><\/div><\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":0,"parent":5685,"menu_order":177,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5102","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/pages\/5102","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/comments?post=5102"}],"version-history":[{"count":3,"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/pages\/5102\/revisions"}],"predecessor-version":[{"id":5105,"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/pages\/5102\/revisions\/5105"}],"up":[{"embeddable":true,"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/pages\/5685"}],"wp:attachment":[{"href":"https:\/\/thoraxzentrum-ruhrgebiet.de\/pl\/wp-json\/wp\/v2\/media?parent=5102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}